The objective of the PPG-GBM is to train high-level professionals with solid knowledge of genetics and molecular biology who can perform activities related to genetics and related areas in public and private institutions and companies. The program has always kept its focus on training human resources, able to act and collaborate in solving society’s problems in the areas of environment, agronomy, and health, in a regionalized context. The program’s mission is broad, which allows us to organize it into topics such as (i) training of personnel for the study and genetic diagnosis related to biodiversity and conservation, production of cultivable varieties, and monitoring of compounds causing genetic damage; (ii) transfer of knowledge to the productive sector, either by the generation of products and technology (such as bioinsecticides, modified plants, and secondary compounds); (iii) support for the health sector, with information related to genetically based diseases such as cancer, as well as the generation of bio-products associated with the control of endemic diseases, such as dengue fever; and (i) contribution to the search for solutions that allow an improvement in the socio-economic quality of the country and the northern region of Paraná, where the PPG-GBM is located, with the generation of bio-based products associated with the control of
To this end, the Graduate Program in Genetics and Molecular Biology operates in three broad lines of research, with faculty members distributed across more than one line. The themes involve both basic and applied sciences, with possibilities of cooperation between laboratories.
Molecular Biology, Omics Methodologies and Applications: Application of omics and molecular biology methodologies for gene expression studies and molecular diagnostics. Genetic engineering, genome editing and characterization of transformed plants. Functional genomics and biological networks applied to plant-pathogen interaction, biological control and production.
Genetic Diversity and Evolution: Studies of genetic diversity in animals, plants and microorganisms, using molecular and cytomolecular tools. Population analysis, evolutionary and conservation genomics, phylogeny and phylogeography, based on molecular markers, DNA barcode and sequencing data. Comparative cell biology, based on morphological, ultrastructural and immunostaining data.
Toxicogenomics, Oncogenetics and Developmental Genetics: Toxicogenomic studies and genomic protection, through cytogenetic, epigenetic and molecular analyses. Tests using natural and xenobiotic compounds, two- and three-dimensional cell cultures, environmental monitoring and human populations. Experimental models applied to reproduction and development. Evaluation of genetic and epigenetic mechanisms as biomarkers of susceptibility and prognosis in malignant tumors.