{"id":733,"date":"2022-08-24T10:32:38","date_gmt":"2022-08-24T13:32:38","guid":{"rendered":"https:\/\/pos.uel.br\/pgcif\/?page_id=733"},"modified":"2022-08-24T10:51:22","modified_gmt":"2022-08-24T13:51:22","slug":"profa-dra-cassia-thais-bussamra-vieira-zaia","status":"publish","type":"page","link":"https:\/\/pos.uel.br\/pgcif\/profa-dra-cassia-thais-bussamra-vieira-zaia\/","title":{"rendered":"Profa. Dra. C\u00e1ssia Tha\u00efs Bussamra Vieira Zaia"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pos.uel.br\/pgcif\/wp-content\/uploads\/2022\/08\/THAIS-2022-1.png\" alt=\"\" class=\"wp-image-740\" width=\"188\" height=\"218\" srcset=\"https:\/\/pos.uel.br\/pgcif\/wp-content\/uploads\/2022\/08\/THAIS-2022-1.png 262w, https:\/\/pos.uel.br\/pgcif\/wp-content\/uploads\/2022\/08\/THAIS-2022-1-259x300.png 259w\" sizes=\"auto, (max-width: 188px) 100vw, 188px\" \/><\/figure>\n\n\n\n<p>LaFiNeM-Laborat\u00f3rio de Fisiologia Neuroend\u00f3crina e Metabolismo<br>ctbvzaia@uel.br<br> (43) 3371-5941<\/p>\n\n\n\n<p><br><strong><em>Linha de Pesquisa<\/em><\/strong>:<\/p>\n\n\n\n<p> Controle neuroend\u00f3crino da homeostase energ\u00e9tica<\/p>\n\n\n\n<p><br><strong><em>Descri\u00e7\u00e3o<\/em><\/strong><br>No LaFiNeM &#8211; Laborat\u00f3rio de Fisiologia Neuroend\u00f3crina e Metabolismo, eu e o Dr. Ernane T. Uch\u00f4a, que faz parte deste laborat\u00f3rio, estudamos,<br>em ratos, as altera\u00e7\u00f5es hormonais e metab\u00f3licas plasm\u00e1ticas envolvendo ingest\u00e3o alimentar, toxicidade e desenvolvimento em diferentes situa\u00e7\u00f5es<br>experimentais. Estudo central: administra\u00e7\u00e3o e determina\u00e7\u00e3o de neuromoduladores. Estudo perif\u00e9rico: utiliza\u00e7\u00e3o de nanopart\u00edculas, herbicidas,<br>fitoter\u00e1picos, vitaminas, estresse, etc. para avalia\u00e7\u00f5es teciduais e plasm\u00e1ticas de metab\u00f3litos e horm\u00f4nios; altera\u00e7\u00f5es no sistema reprodutor e<br>avalia\u00e7\u00e3o metab\u00f3licas e de interfer\u00eancia em proles (DOHaD). Trabalhamos em conjunto com outros laborat\u00f3rios para an\u00e1lises de nosso dados:<br>bioqu\u00edmicas e produ\u00e7\u00e3o de nanopart\u00edculas, no Laborat\u00f3rio de Qu\u00edmica Prebi\u00f3tica-LQP-QUI-UEL, do Dr. Dimas A.M. Zaia; fluorimetria e estresse<br>oxidativo, no Laborat\u00f3rio de Ecofisiologia Animal-LEFA-CCB-UEL da Dr. Cl\u00e1udia B.R. Martinez, e no Lab. de Toxicologia e Dist\u00farbios<br>Metab\u00f3licos da Reprodu\u00e7\u00e3o da Dra. Glaura S.A. Fernandes; an\u00e1lises reprodutoras, no Laborat\u00f3rio de Farmacologia da Dra. Daniela C.C.G.<br>Cantamessa e no laborat\u00f3rio da Dra. Glaura; an\u00e1lises histol\u00f3gicas de \u00f3rg\u00e3os e tecidos no Laborat\u00f3rio de An\u00e1lise Histopatol\u00f3gica-LaHIP-HIT-UEL,<br>do Dr. F\u00e1bio G. Andrade. Fazemos colabora\u00e7\u00f5es realizando an\u00e1lises bioqu\u00edmicas: Laborat\u00f3rio de Fisiologia Metab\u00f3lica, da Dra. Gisele L. Bertoline<br>e Dra. Helenir M. Souza, e Laborat\u00f3rio de Farmacologia Vascular, da Dra. Graziela S. Ceravolo. Tamb\u00e9m colaboramos com o Dr. Dimas, na \u00e1rea de<br>Qu\u00edmica Prebi\u00f3tica, orientando alunos e fazendo testes biol\u00f3gicos de materiais avaliando benef\u00edcios e toxicidade. De todas essas colabora\u00e7\u00f5es, temos<br>v\u00e1rias produ\u00e7\u00f5es: artigos cient\u00edficos, artigos de divulga\u00e7\u00e3o, review e cap\u00edtulos de livros. Algumas produ\u00e7\u00f5es dos \u00faltimos anos est\u00e3o a seguir.<br><br><strong><em>Principais trabalhos<\/em><\/strong><\/p>\n\n\n\n<p>ZAIA, C\u00c1SSIA THA\u00cfS B. V., UCH\u00d4A,.ERNANE T., SANTOS, ANGELO A. T., RIBEIRO, RACHEL C. A., BATISTA, ANA C. S.,<br>CRESPIGIO, JEFFERSON, UTIDA, LAWRENCE, MOURA, GALIANO B., BROWNLOW, MILENE L., GARNICA-SIQUEIRA, MARCELA<br>C., REIS, WAGNER L., ANTUNES-RODRIGUES, JOSE, ZAIA, DIMAS A. M. Vasoactive intestinal peptide promotes hypophagia and metabolic<br>changes: role of paraventricular hypothalamic nucleus and nitric oxide. BRAIN RESEARCH BULLETIN, S-22-00087, 2022.<\/p>\n\n\n\n<p>MARTINS, ANDRESSA BUSETTI; BROWNLOW, MILENE LARA; ARA\u00daJO, BRUNO BLANCO; GARNICA-SIQUEIRA, MARCELA<br>CRISTINA; ZAIA, Dimas Augusto Morozin; LEITE, CRISTIANE MOTA; ZAIA, C\u00c1SSIA THA\u00cfS BUSSAMRA VIEIRA; UCHOA, ERNANE<br>TORRES. Arcuate nucleus of the hypothalamus contributes to the hypophagic effect and plasma metabolic changes induced by vasoactive intestinal<br>peptide and pituitary adenylate cyclase-activating polypeptide. NEUROCHEMISTRY INTERNATIONAL, v.155, p.105300, 2022.<\/p>\n\n\n\n<p>DE SOUZA, CAMILA F.; STOPA, LARISSA RUGILA S.; MARTINS, ANDRESSA B.; WUNDERLICH, ANA LUIZA M.; LOPES,<br>GABRIELA MENDICELLI; ZAIA, DIMAS A.M.; ZAIA, CASSIA THA\u00cfS B.V.; DE ANDRADE, F\u00c1BIO GOULART; LEITE, CRISTIANE<br>MOTA; UCHOA, ERNANE TORRES. actation overnutrition-induced obesity impairs effects of exogenous corticosterone on energy homeostasis<br>and hypothalamic-pituitary-adrenal axis in male rats. LIFE SCIENCES, v.304, p.120721 &#8211; , 2022.<\/p>\n\n\n\n<p>SOUZA GALIA, WINNY BEATRIZ; BIAZI, GIULIANA REGINA; FRASSON&#8217;UEMURA, ISABELE GON\u00c7ALVES; MIKSZA, DANIELE<br>ROMANI; ZAIA, C\u00c1SSIA THA\u00cfS BUSSAMRA VIEIRA; ZAIA, Dimas Augusto Morozin; SOUZA, HELENIR MEDRI; BERTOLINI, GISELE<br>LOPES. Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late<br>sepsis. CELL BIOCHEMISTRY AND FUNCTION, v.39, p.754 &#8211; 762, 2021.<\/p>\n\n\n\n<p>STOPA, LARISSA RUGILA S.; DE SOUZA, CAMILA F.; MARTINS, ANDRESSA B.; LOPES, GABRIELA MENDICELLI; COSTA,<br>NATH\u00c1LIA O.; GERARDIN, DANIELA C. CECCATTO; DE CARVALHO, GIOVANA GOMES; ZAIA, Dimas Augusto Morozin; ZAIA,<br>C\u00c1SSIA THA\u00cfS B.V.; UCHOA, ERNANE TORRES; LEITE, CRISTIANE MOTA. Neonatal overfeeding reduces estradiol plasma levels and<br>disrupts noradrenergic-kisspeptin-GnRH pathway and fertility in adult female rats. MOLECULAR AND CELLULAR ENDOCRINOLOGY, v.524,<br>p.111147, 2021.<\/p>\n\n\n\n<p>ZAIA, DIMAS A. M.; ZAIA, C\u00c1SSIA THA\u00cfS B. V. A Few Experimental Suggestions Using Minerals to Obtain Peptides with a High<br>Concentration of L-Amino Acids and Protein Amino Acids. Symmetry-Basel, v.12, p.2046, 2020.<\/p>\n\n\n\n<p>NOVI, DANIELLA R. B. S.; VIDIGAL, CAMILA B.; MARQUES, BRUNO V. D.; FORCATO, SIMONE; RAQUEL, HIVINY A.; ZAIA,<br>DIMAS A. M.; ZAIA, C\u00c1SSIA T. B. V.; MARTINS-PINGE, MARLI C.; GERARDIN, DANIELA C. C.; CERAVOLO, GRAZIELA S. Can<br>maternal treatment with metformin during gestation and lactation cause metabolic and cardiovascular disorders in rat offspring?. ARCHIVES OF<br>PHYSIOLOGY AND BIOCHEMISTRY, v.126, p.276-281, 2020.<\/p>\n\n\n\n<p>ZAIA, DIMAS A. M.; DE CARVALHO, PAULO C. G.; SAMULEWSKI, RAFAEL B.; DE CARVALHO PEREIRA, RODRIGO; ZAIA,<br>C\u00c1SSIA THA\u00cfS B.V. Unexpected Thiocyanate Adsorption onto Ferrihydrite Under Prebiotic Chemistry Conditions. ORIGINS OF LIFE AND<br>EVOLUTION OF BIOSPHERES, v.50, p.57-76, 2020.<\/p>\n\n\n\n<p>GARNICA-SIQUEIRA, MARCELA C.; MARTINS, A. B.; STOPA, LARISSA RUGILA S.; DE SOUZA, CAMILA F.; ZAIA, DIMAS A. M.;<br>LEITE, CRISTIANE MOTA; ZAIA, C. T. B. V.; UCH\u00d4A, Ernane Torres. Adrenalectomy impairs vasoactive intestinal peptide-induced changes in<br>food intake and plasma parameters. ENDOCRINE. , p.675 &#8211; 682, 2019.<\/p>\n\n\n\n<p>DE SOUZA, CAMILA F.; STOPA, LARISSA RUGILA S.; SANTOS, GEISIELLE FERNANDES; TAKASUMI, LETICIA CORREA N.;<br>MARTINS, ANDRESSA B.; GARNICA-SIQUEIRA, MARCELA C.; FERREIRA, RENAN NASCIMENTO; DE ANDRADE, F\u00c1BIO<br>GOULART; LEITE, CRISTIANE MOTA; ZAIA, DIMAS A.M.; ZAIA, C\u00c1SSIA THA\u00cfS B.V.; UCHOA, ERNANE TORRES. Estradiol protects<br>against ovariectomy-induced susceptibility to the anabolic effects of glucocorticoids in rats. LIFE SCIENCES, v.218, p.185-196, 2019.<\/p>\n\n\n\n<p>STOPA, LARISSA RUGILA S.; DE SOUZA, CAMILA F.; SANTOS, GEISIELLE FERNANDES; MARTINS, ANDRESSA B.; FERREIRA,<br>RENAN NASCIMENTO; DE ANDRADE, F\u00c1BIO GOULART; LEITE, CRISTIANE MOTA; ZAIA, DIMAS A.M.; ZAIA, CASSIA THA\u00cfS<br>B.V.; UCHOA, ERNANE TORRES. Sex differences in glucocorticoids-induced anabolic effects in rats. PHYSIOLOGY &amp; BEHAVIOR, v.209,<br>p.112587, 2019.<\/p>\n\n\n\n<p>PEREIRA, RODRIGO C.; ANIZELLI, PEDRO R.; DI MAURO, EDUARDO; VALEZI, DANIEL F.; DA COSTA, ANTONIO CARLOS S.;<br>ZAIA, C\u00c1SSIA THA\u00cfS B. V.; ZAIA, DIMAS A. M. The effect of pH and ionic strength on the adsorption of glyphosate onto ferrihydrite.<br>GEOCHEMICAL TRANSACTIONS, v.20, p.1-14, 2019.<\/p>\n\n\n\n<p>GARNICA-SIQUEIRA, MARCELA CRISTINA; MARTINS, ANDRESSA BUSETTI; ZAIA, Dimas Augusto Morozin; LEITE, CRISTIANE<br>MOTA; UCH\u00d4A, Ernane Torres; ZAIA, C\u00c1SSIA THA\u00cfS BUSSAMRA VIEIRA. Corticotrophin-releasing factor mediates vasoactive intestinal<br>peptide-induced hypophagia and changes in plasma parameters. HORMONES AND BEHAVIOR, v.105, p.138-145, 2018.<\/p>\n\n\n\n<p>MARTINS, ANDRESSA B.; GARNICA-SIQUEIRA, MARCELA C.; ZAIA, DIMAS A. M.; ZAIA, C\u00c1SSIA THA\u00cfS B. V.; UCH\u00d4A,<br>ERNANE T. Oxytocin participates on the effects of vasoactive intestinal peptide on food intake and plasma parameters. Molecular and Cellular<br>Biochemistry, v.437, p.177-183, 2018.<br>cap\u00edtulos de livros:<br>ZAIA, C.T.B.V.; UCH\u00d4A, E.T. Sistema nervoso aut\u00f4nomo e seu controle central, cap. 18. In: Rui Curi e Joaquim Proc\u00f3pio (Orgs.). Fisiologia<br>b\u00e1sica. 2. ed. Rio de Janeiro: Guanabara Koogan, 2017.<br>ZAIA, C.T.B.V. Visualizando citologicamente o ciclo estral. Estudando a a\u00e7\u00e3o dos ester\u00f3ides gonadais. Entendendo o papel da adrenalina no<br>exerc\u00edcio. ZAIA C.T.B.V.; ZAIA, D.A.M. Digerindo A\u00e7\u00facares. In: Rui Curi, Joaquim Proc\u00f3pio e Luiz Cl\u00e1udio Fernandes (Orgs.). Praticando<br>Fisiologia. 1. ed. Barueri-SP: Manole, 2005, p. 217-220, 221-227, 437-441; 259-263<br>ZAIA, D.A.M.; ZAIA, C.T.B.V.; CARNEIRO, C.E.A. Qu\u00edmica Prebi\u00f3tica: a qu\u00edmica da origem da vida, p. 95-113. In: Douglas Galante, Evandro<br>Pereira da Silva, F\u00e1bio Rodrigues, Jorge E. Horvath e Marcio G. B. de Avellar (Orgs.). Astrobiologia: uma ci\u00eancia emergente. 1. ed. S\u00e3o Paulo:<br>Tikinet edi\u00e7\u00e3o\/IAG-USP, 2016.<br>ZAIA, C.T.B.V.; ZAIA, D.A.M. SOUZA, R.F. Prote\u00ednas e a origem da vida, p. 191-197; ZAIA, C.T.B.V.; ZAIA, D.A.M. Espectrofotometria para<br>an\u00e1lise de prote\u00ednas totais, p. 217-221. In: Rozangela Verlengia, Rui Curi, Estela Bevilacqua e Philip Newsholme (Orgs.). An\u00e1lises de RNA,<br>prote\u00ednas e matab\u00f3litos: metodologias e procedimentos t\u00e9cnicos. 1. ed. Rio de Janeiro: Editora Grupo GEN, 2012.<\/p>\n\n\n\n\n\n\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-3 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\n\n\n\n\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>LaFiNeM-Laborat\u00f3rio de Fisiologia Neuroend\u00f3crina e Metabolismoctbvzaia@uel.br (43) 3371-5941 Linha de Pesquisa: Controle neuroend\u00f3crino da homeostase energ\u00e9tica Descri\u00e7\u00e3oNo LaFiNeM &#8211; Laborat\u00f3rio de Fisiologia Neuroend\u00f3crina e Metabolismo, eu e o Dr. Ernane T. Uch\u00f4a, que faz parte deste laborat\u00f3rio, estudamos,em ratos, as altera\u00e7\u00f5es hormonais e metab\u00f3licas plasm\u00e1ticas envolvendo ingest\u00e3o alimentar, toxicidade e desenvolvimento em diferentes situa\u00e7\u00f5esexperimentais. Estudo [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-733","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/pages\/733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/comments?post=733"}],"version-history":[{"count":5,"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/pages\/733\/revisions"}],"predecessor-version":[{"id":742,"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/pages\/733\/revisions\/742"}],"wp:attachment":[{"href":"https:\/\/pos.uel.br\/pgcif\/wp-json\/wp\/v2\/media?parent=733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}